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Chemical Structure : MMI-0100
CAS No.: 1039342-24-9
Catalog No.: PC-38783Not For Human Use, Lab Use Only.
MMI-0100 is a cell-permeant peptide inhibitor of MAPKAP kinase 2 (MK2), inhibits MK2 and downstream fibrosis and inflammation.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $178 | In stock | |
| 10 mg | $288 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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MMI-0100 is a cell-permeant peptide inhibitor of MAPKAP kinase 2 (MK2), inhibits MK2 and downstream fibrosis and inflammation.
MMI-0100 prevents vein graft intimal thickening ex vivo and in vivo.
MMI-0100 inhibits cardiac fibrosis in myocardial infarction by direct actions on cardiomyocytes and fibroblasts via MK2 inhibition.
MMI-0100 treatment reduced cardiac fibrosis, decreased cardiac hypertrophy, and prolonged survival in fibrotic cMyBPC40k disease mice model.
| M.Wt | 2283.64 | |
| Formula | C98H171N37O26 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
5 mM in PBS |
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| Chemical Name/SMILES |
L-Alanine, L-tyrosyl-L-alanyl-L-arginyl-L-alanyl-L-alanyl-L-alanyl-L-arginyl-L-glutaminyl-L-alanyl-L-arginyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-alanyl-L-arginyl-L-glutaminyl-L-leucylglycyl-L-valyl-L-alanyl- |
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1. Akihito Muto, et al. Vascul Pharmacol. Jan-Feb 2012;56(1-2):47-55.
2. Meng Q, et al. J Am Heart Assoc. 2017 Sep 4;6(9):e006590.
3. Xu L, et al. J Mol Cell Cardiol. 2014 Dec;77:86-101.
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