MMV667492 | Ezrin inhibitor | ProbeChem Biochemicals

Chemical Structure : MMV667492

MMV667492 (MMV 667492, MMV-667492)

Catalog No.: PC-70130Not For Human Use, Lab Use Only.

MMV667492 is a novel potent Ezrin inhibitor with Kd of 29.4 nM.

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Biological Activity

MMV667492 is a novel potent Ezrin inhibitor with Kd of 29.4 nM.
MMV-667492 exhibits potent anti-ezrin activity in all biologic assays and has better physicochemical properties for drug-likeness than NSC305787.
MMV-667492 is a novel antimetastatic agent for the treatment of metastatic osteosarcoma.

Physicochemical Properties

M.Wt	313.357
Formula	C17H19N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(cyclohexylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-N-methylnitrous amide

References

1. Çelik H, et al. Mol Cancer Ther. 2015 Nov;14(11):2497-507.

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MMV667492 (MMV 667492, MMV-667492)

Biological Activity

Physicochemical Properties

References

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