Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : MPD2
Catalog No.: PC-22155Not For Human Use, Lab Use Only.
MPD2 is a first-in-class PROTAC degrader of SARS-CoV-2 MPro, effectively reduces MPro protein levels in 293T cells with DC50 of 296 nM on a time-dependent, CRBN-mediated, and proteasome-driven mechanism.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
MPD2 is a first-in-class PROTAC degrader of SARS-CoV-2 MPro, effectively reduces MPro protein levels in 293T cells with DC50 of 296 nM on a time-dependent, CRBN-mediated, and proteasome-driven mechanism.
MPD2 exhibits promising antiviral activity against various SARS-CoV-2 strains and exhibiting enhanced potency against nirmatrelvir-resistant viruses.
| M.Wt | 973.13 | |
| Formula | C51H68N6O13 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Alugubelli YR, et al. J Med Chem. 2024 Apr 12. doi: 10.1021/acs.jmedchem.3c02416.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
