MRE-269 |CAS:475085-57-5 Probechem Biochemicals

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Chemical Structure : MRE-269

CAS No.: 475085-57-5

MRE-269 (ACT-333679, ACT333679)

Catalog No.: PC-46004Not For Human Use, Lab Use Only.

MRE-269 (ACT-333679) is a potent, selective IP receptor (prostaglandin I2 receptor) agonist with Ki of 20 nM.

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25 mg	$198	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

MRE-269 (ACT-333679) is a potent, selective IP receptor (prostaglandin I2 receptor) agonist with Ki of 20 nM.
MRE-269 displays no significant affinity for other prostanoid receptors (Ki>2.6 uM).
MRE-269 is the activve metabolite of Selexipag (NS-304).

Physicochemical Properties

M.Wt	419.5161
Formula	C25H29N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: ≥ 51 mg/mL
Chemical Name/SMILES	Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)(1-methylethyl)amino]butoxy]-

References

1. Kuwano K, et al. J Pharmacol Exp Ther. 2007 Sep;322(3):1181-8.

2. Kuwano K, et al. J Pharmacol Exp Ther. 2008 Sep;326(3):691-9.

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MRE-269 (ACT-333679, ACT333679)

Biological Activity

Physicochemical Properties

References

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