MRGPRX1 agonist 1 |CAS:2377379-39-8 Probechem Biochemicals

Chemical Structure : MRGPRX1 agonist 1

CAS No.: 2377379-39-8

MRGPRX1 agonist 1

Catalog No.: PC-38066Not For Human Use, Lab Use Only.

MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist with EC50 of 50 nM, superior selectivity over opioid receptors.

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5 mg	$228	In stock
10 mg	$358	In stock
25 mg	$548	In stock
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Biological Activity

MRGPRX1 agonist 1 is a highly potent MRGPRX1 agonist with EC50 of 50 nM, superior selectivity over opioid receptors.
MRGPRX1 agonist 1 displays favorable distribution to the spinal cord, the presumed site of action for the MRGPRX1-mediated analgesic effects.

Physicochemical Properties

M.Wt	435.498
Formula	C23H21N3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(1-aminoisoquinolin-6-yloxy)-4-methylphenyl)-2-methoxybenzenesulfonamide

References

1. Prchalová E, et al. J Med Chem. 2019 Sep 26;62(18):8631-8641.

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