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Chemical Structure : MRL-1237
Catalog No.: PC-62926Not For Human Use, Lab Use Only.
MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
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MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein.
MRL-1237 inhibits poliovirus-specific RNA synthesis in HeLa cells infected with a wild strain but not with an F164Y mutant.
| M.Wt | 354.813 | |
| Formula | C19H16ClFN4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Shimizu H, et al. J Virol. 2000 May;74(9):4146-54.
2. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30.
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