MS48107 | GPR68 PAM | Probechem Biochemicals

Chemical Structure : MS48107

CAS No.: 2375070-79-2

MS48107 (MS 48107)

Catalog No.: PC-72990Not For Human Use, Lab Use Only.

MS48107 (MS 48107) is a potent, selective, positive allosteric modulator of G protein-coupled receptor 68 (GPR68, Log(αβ/KB)=6.83).

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10 mg	$148	In stock
25 mg	$268	In stock
50 mg	$428	In stock
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Biological Activity

MS48107 (MS 48107) is a potent, selective, positive allosteric modulator of G protein-coupled receptor 68 (GPR68, Log(αβ/KB)=6.83).
MS48107 displays good selectivity against all human GPCRome in PRESTO-Tango screening assays.
MS48107 was bioavailable and brain-penetrant in mice.

Physicochemical Properties

M.Wt	417.444
Formula	C23H20FN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-(4-Amino-6-((4-phenoxybenzyl)amino)-1,3,5-triazin-2-yl)-3-fluorophenyl)methanol

References

1. Xufen Yu, et al. J Med Chem. 2019 Aug 22;62(16):7557-7574.

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MS48107 (MS 48107)

Biological Activity

Physicochemical Properties

References

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