MS7829 | cGAS DUBTAC | Probechem Biochemicals

Chemical Structure : MS7829

MS7829 (MS 7829)

Catalog No.: PC-22954Not For Human Use, Lab Use Only.

MS7829 is a first-in-class DUBTAC of cGAS, a key component of the cGAS-STING pathway, stabilizes cGAS and increases the cGAS downstream effector protein STING.

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Biological Activity

MS7829 is a first-in-class DUBTAC of cGAS, a key component of the cGAS-STING pathway, stabilizes cGAS and increases the cGAS downstream effector protein STING.

Physicochemical Properties

M.Wt	898.95
Formula	C43H57Cl2N9O6S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N-(8-(2-(3-(6,7-dichloro-2-(2-hydroxyacetyl)-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indol-9-yl)-1H-pyrazol-1-yl)acetamido)octyl)-3-(5-(4-(4-(dimethylamino)but-2-enoyl)-2-oxopiperazin-1-yl)thiophen-2-yl)propanamide

References

1. Jin J, et al. Angew Chem Int Ed Engl. 2024 Aug 16:e202415168.

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MS7829 (MS 7829)

Biological Activity

Physicochemical Properties

References

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