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Chemical Structure : MSA-2
CAS No.: 129425-81-6
Catalog No.: PC-73371Not For Human Use, Lab Use Only.
MSA-2 is a potent and orally available non-nucleotide STING agonist with EC50 of 8.3 and 24 uM for human STING isoforms WT and HAQ, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $498 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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MSA-2 is a potent and orally available non-nucleotide STING agonist with EC50 of 8.3 and 24 uM for human STING isoforms WT and HAQ, respectively.
MSA-2 exhibits antitumor activity and stimulates interferon-β secretion in tumors.
MSA-2 induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models.
| M.Wt | 294.32 | |
| Formula | C14H14O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid |
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1. Bo-Sheng Pan, et al. Science. 2020 Aug 21;369(6506):eaba6098.
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