MSC-4106 | TEAD inhibitor | Probechem Biochemicals

Chemical Structure : MSC-4106

CAS No.: 2738542-58-8

MSC-4106 (MSC4106)

Catalog No.: PC-47086Not For Human Use, Lab Use Only.

MSC-4106 is a potent, in vivo active inhibitor of TEAD transcription factor with IC50 of 4 and 14 nM in SK-HEP1 reporter and NCI-H226 viability assays, respectively.

Packing	Price	Stock
5 mg	$238	In stock
10 mg	$388	In stock
25 mg	$598	In stock
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

Welcome credit card payment!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Biological Activity

MSC-4106 is a potent, in vivo active inhibitor of TEAD transcription factor with IC50 of 4 and 14 nM in SK-HEP1 reporter and NCI-H226 viability assays, respectively.
MSC-4106 binds to TEAD P-site.
MSC-4106 exhibits desirable potency, mouse pharmacokinetic properties, and in vivo efficacy.

Physicochemical Properties

M.Wt	359.308
Formula	C18H12F3N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-methyl-8-(4-(trifluoromethyl)phenyl)-2,8-dihydropyrazolo[3,4-b]indole-5-carboxylic acid

References

1. Heinrich T, et al. J Med Chem. 2022 Jun 28. doi: 10.1021/acs.jmedchem.2c00403.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

MSC-4106 (MSC4106)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.