MSD-914 | ACHY inhibitor | Probechem Biochemicals

Chemical Structure : MSD-914

MSD-914 (MSD914)

Catalog No.: PC-26077Not For Human Use, Lab Use Only.

MSD-914 is a potent, selective S-adenosylhomocysteine hydrolase (AHCY) inhibitor with IC50 of 40 nM, shows broad-spectrum in vitro anti-filovirus activity against EBOV, Marburg virus, and Sudan ebolavirus.

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Biological Activity

Physicochemical Properties

M.Wt	250.28
Formula	C11H15FN6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,2R,3R)-3-(4-amino-7-fluoro-1H-imidazo[4,5-c]pyridin-1-yl)cyclopentane-1,2-diamine

References

1. Antonella Converso, et al. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2737-40.

2. Johnston SC, et al. PLoS One. 2026 Feb 6;21(2):e0340118.

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MSD-914 (MSD914)

Biological Activity

Physicochemical Properties

References

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