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Chemical Structure : MT-031
Catalog No.: PC-60449Not For Human Use, Lab Use Only.
A potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo.
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MT-031 (MT031) is a potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo.
MT-031 inhibits H2O2-induced neurotoxicity in human neuroblastoma SH-SY5Y cells, and antagonizes scopolamine-induced memory and cognitive impairments in mice.
MT-031 upregulates mRNA expression levels of Bcl-2, the neurotrophic factors and the anti-inflammatory cytokine, Ntrk, and down-regulates the mRNA expression levels of IL-6 in scopolamine-induced mice.
| M.Wt | 274.364 | |
| Formula | C16H22N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Liu W, et al. Neuropharmacology. 2017 Feb;113(Pt A):445-456.
2. Liu W, et al. Neuropharmacology. 2016 Oct;109:376-385.
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