MT-031 |CAS:1802158-63-9 Probechem Biochemicals

Chemical Structure : MT-031

MT-031 (MT 031;MT031)

Catalog No.: PC-60449Not For Human Use, Lab Use Only.

A potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo.

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Biological Activity

MT-031 (MT031) is a potent, brain penetrant, dual MAO-A and AChE inhibitor that shows neuroprotective effects both in vitro and in vivo.
MT-031 inhibits H2O2-induced neurotoxicity in human neuroblastoma SH-SY5Y cells, and antagonizes scopolamine-induced memory and cognitive impairments in mice.
MT-031 upregulates mRNA expression levels of Bcl-2, the neurotrophic factors and the anti-inflammatory cytokine, Ntrk, and down-regulates the mRNA expression levels of IL-6 in scopolamine-induced mice.

Physicochemical Properties

M.Wt	274.364
Formula	C16H22N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-Ethyl-methyl-carbamic acid 3-[1-(methyl-prop-2-ynyl-amino)-ethyl]-phenyl ester

References

1. Liu W, et al. Neuropharmacology. 2017 Feb;113(Pt A):445-456.

2. Liu W, et al. Neuropharmacology. 2016 Oct;109:376-385.

MT-031 (MT 031;MT031)

Biological Activity

Physicochemical Properties

References

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