MT-189 | CLC-K inhibitor | Probechem Biochemicals

Chemical Structure : MT-189

Catalog No.: PC-27986Not For Human Use, Lab Use Only.

MT-189 is a specific small molecule inhibitor of chloride channel CLC-Ka (CLCNKA) with IC50 of 7.0 uM, 3-fold selectivity for CLC-Ka over CLC-Kb.

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Biological Activity

MT-189 is a specific small molecule inhibitor of chloride channel CLC-Ka (CLCNKA) with IC50 of 7.0 uM, 3-fold selectivity for CLC-Ka over CLC-Kb.

M.Wt	307.13
Formula	C15H8Cl2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-chloro-3-(2-chlorophenyl)benzofuran-2-carboxylic acid

1. Koster AK, et al. Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4900-E4909.

2. Liantonio A, et al. J Hypertens. 2012 Jan;30(1):153-67.