MTX-211 |Cas:1952236-05-3 Buy MTX-211 from ProbeChem, Global Biochemicals Supplier

Chemical Structure : MTX-211

CAS No.: 1952236-05-3

MTX-211 (MTX 211, Mol 211)

Catalog No.: PC-70200Not For Human Use, Lab Use Only.

MTX-211 is a first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with IC50 of <100 nM.

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Biological Activity

MTX-211 is a first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with IC50 of <100 nM.
MTX-211 demonstrated in vivo anticancer activity against multiple KRAS mutant colorectal tumors.
MTX-211 shows limited off-target toxicity and a broad therapeutic window.

Physicochemical Properties

M.Wt	478.323
Formula	C20H14Cl2FN5O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Methanesulfonamide, N-[2-chloro-5-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-3-pyridinyl]-

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MTX-211 (MTX 211, Mol 211)

Biological Activity

Physicochemical Properties

References

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