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MU1742

Chemical Structure : MU1742

CAS No.:

MU1742 (MU-1742)

Catalog No.: PC-23900Not For Human Use, Lab Use Only.

MU1742 is a potent, selective inhibitor of Casein kinases 1 (CK1) with IC50 of 7/6/28 nM for CK1α/CK1δ/CK1ε respectively, does not inhibit p38α.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MU1742 is a potent, selective inhibitor of Casein kinases 1 (CK1) with IC50 of 7/6/28 nM for CK1α/CK1δ/CK1ε respectively, does not inhibit p38α.

Physicochemical Properties

M.Wt 408.46
Formula C22H22F2N6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(1-((4-fluoro-1-methylpiperidin-4-yl)methyl)-4-(5-fluoropyridin-2-yl)-1H-imidazol-5-yl)-1H-pyrrolo[2,3-b]pyridine

References

1. Václav Němec, et al. Angew Chem Int Ed Engl. 2023 Mar 6;62(11):e202217532.

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