MU1787 | HIPK inhibitor | Probechem Biochemicals

Chemical Structure : MU1787

MU1787 (MU 1787)

Catalog No.: PC-73294Not For Human Use, Lab Use Only.

MU1787 is a potent, highly selective Homeodomain-interacting protein kinases (HIPKs) inhibitor with IC50 of 285/123/283 nM for HIPK1/2/3, repectively.

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Biological Activity

MU1787 is a potent, highly selective Homeodomain-interacting protein kinases (HIPKs) inhibitor with IC50 of 285/123/283 nM for HIPK1/2/3, repectively.
MU1787 is highly selective across the kinome in a broad panel of 373 human kinases, does not inhibits HIPK4 at 10 uM.

Physicochemical Properties

M.Wt	318.380
Formula	C19H18N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-[4-(1,1-Dimethylethyl)phenyl]-5-(1H-1,2,3-triazol-5-yl)furo[3,2-b]pyridine

References

1. Václav Němec, et al. Eur J Med Chem. 2021 Apr 5;215:113299.

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MU1787 (MU 1787)

Biological Activity

Physicochemical Properties

References

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