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Chemical Structure : MX106
Catalog No.: PC-35080Not For Human Use, Lab Use Only.
MX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM.
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MX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM.
MX106 significantly enhances the tumoricidal efficacy of doxorubicin in TNBC cells,.
MX106 induces degradation of XIAP and/or cIAP1, which inhibited NF-κB activation by genotoxic agents.
| M.Wt | 390.527 | |
| Formula | C25H30N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Wang W, et al. J Pharmacol Exp Ther. 2018 May 7. pii: jpet.118.249151.
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