MX106 |CAS:2170836-81-2 Probechem Biochemicals

Chemical Structure : MX106

MX106 (MX 106)

Catalog No.: PC-35080Not For Human Use, Lab Use Only.

MX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM.

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Biological Activity

MX106 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 2.2 uM.
MX106 significantly enhances the tumoricidal efficacy of doxorubicin in TNBC cells,.
MX106 induces degradation of XIAP and/or cIAP1, which inhibited NF-κB activation by genotoxic agents.

Physicochemical Properties

M.Wt	390.527
Formula	C25H30N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(((4-isopropylbenzyl)oxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol

References

1. Wang W, et al. J Pharmacol Exp Ther. 2018 May 7. pii: jpet.118.249151.

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MX106 (MX 106)

Biological Activity

Physicochemical Properties

References

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