Macotirom

Chemical Structure : Macotirom

Catalog No.: PC-27474Not For Human Use, Lab Use Only.

Macotirom is a potent, selective and liver-targeting thyroid hormone receptor beta (THRβ) agonist.

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Biological Activity

Macotirom is a potent, selective and liver-targeting thyroid hormone receptor beta (THRβ) agonist.

M.Wt	566.31
Formula	C19H15Cl2F2N5O7S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-{2,6-dichloro-4-[6-(difluoromethyl)-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)yl]phenoxy}-5-hydroxy-N-(trans-3-hydroxycyclobutyl)pyridine-4-sulfonamide

1. Patent WO2021143706 A1 2021-07-22.