Magnesium isoglycyrrhizinate hydrate | STAT3 inhibitor

Chemical Structure : Magnesium isoglycyrrhizinate hydrate

CAS No.: 658701-67-8

Magnesium isoglycyrrhizinate hydrate (MgIG)

Catalog No.: PC-26387Not For Human Use, Lab Use Only.

Magnesium isoglycyrrhizinate (MgIG) is a stereoisomer of glycyrrhizic acid with more potent hepatoprotective activity and less side effects than glycyrrhizic acid, inhibits inflammatory response through STAT3 pathway, also inhibits the activation of the LPS/TLRs/NF-κB signaling pathway in liver injury caused by anti-tuberculosis (anti-TB) drugs.

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10 mg	$98	In stock
25 mg	$158	In stock
50 mg	$258	In stock
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Biological Activity

Physicochemical Properties

M.Wt	919.30
Formula	C42H62O16.4H2O.Mg
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3S,4S,5R,6R)-6-(((2S,3R,4S,5S,6S)-6-carboxy-2-(((3S,4aR,6aR,6bS,8aS,11S,12aS,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid, magnesium salt hydrate

References

1. Tang GH, et al. World J Gastroenterol. 2015 Nov 21;21(43):12370-80.

2. Xie C, et al. Inflammation. 2015 Aug;38(4):1639-48.

3. Sun L, et al. J Clin Pharmacol. 2007 Jun;47(6):767-73.

Magnesium isoglycyrrhizinate hydrate (MgIG)

Biological Activity

Physicochemical Properties

References

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