Magrolimab |CAS:2169232-81-7 Probechem Biochemicals

Chemical Structure : Magrolimab

CAS No.:

Magrolimab (Anti-human CD47 mAb, human IgG4-Kappa)

Catalog No.: PC-Ab1002Not For Human Use, Lab Use Only.

A monoclonal anti-human CD47 antibody by grafting its complementarity determining regions (CDRs) onto a human IgG4 format.

Packing	Price	Stock
1 mg	$358	In stock
5 mg	$758	In stock
10 mg	$1280	In stock
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Biological Activity

A monoclonal anti-human CD47 antibody by grafting its complementarity determining regions (CDRs) onto a human IgG4 format; bound to monomeric human CD47 with an 8 nM affinity; induced potent macrophage-mediated phagocytosis of primary human AML cells in vitro and completely eradicated human AML in vivo, leading to long-term disease-free survival of patient-derived xenografts.

Physicochemical Properties

M.Wt
Formula	Human IgG4-Kappa
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

References

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Magrolimab (Anti-human CD47 mAb, human IgG4-Kappa)

Biological Activity

Physicochemical Properties

References

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