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Mc-Val-Cit-PABC-PNP

Chemical Structure : Mc-Val-Cit-PABC-PNP

CAS No.: 159857-81-5

Mc-Val-Cit-PABC-PNP (Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate)

Catalog No.: PC-45783Not For Human Use, Lab Use Only.

Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker for ADC design.

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100 mg $58 In stock
250 mg $98 In stock
1 g $158 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Mc-Val-Cit-PABC-PNP is a cathepsin cleavable ADC peptide linker for ADC design.

Physicochemical Properties

M.Wt 737.7562
Formula C35H43N7O11
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 37 mg/mL

Chemical Name/SMILES

L-Ornithinamide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

References

1. Dubowchik GM, et al. Bioconjug Chem. 2002 Jul-Aug;13(4):855-69.

2. Doronina SO, et al. Bioconjug Chem. 2008 Oct;19(10):1960-3.

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