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Mcl1-IN-2

Chemical Structure : Mcl1-IN-2

CAS No.: 292057-76-2

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Mcl1-IN-2 (IMB-XH1)

Catalog No.: PC-43235Not For Human Use, Lab Use Only.

Mcl1-IN-2 (IMB-XH1) is an Mcl-1 inhibitor without a reported IC50 value, also is a non-competitive Delhi metallo-β-lactamase (NDM-1) inhibitor with IC50 of 0.46 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Mcl1-IN-2 (IMB-XH1) is an Mcl-1 inhibitor without a reported IC50 value, also is a non-competitive Delhi metallo-β-lactamase (NDM-1) inhibitor with IC50 of 0.46 uM.

Physicochemical Properties

M.Wt 333.4069
Formula C19H15N3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

8-Quinolinol, 7-[(2-pyridinylamino)-2-thienylmethyl]-

References

1. Richard DJ, et al. Bioorg Med Chem. 2013 Nov 1;21(21):6642-9.

2. Zaneta Nikolovska-Coleska, et al. Discovery and characterization of new small-molecule inhibitors of Mcl-1 by high-throughput screening. AACR 2008.

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