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Chemical Structure : Mcl1-IN-26
Catalog No.: PC-60153Not For Human Use, Lab Use Only.
Mcl-1-IN-26 is a potent, selective Mcl-1 inhibitor with IC50 of <3 nM in FRET assays.
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Mcl-1-IN-26 is a potent, selective Mcl-1 inhibitor with IC50 of <3 nM in FRET assays.
Mcl-1-IN-26 displays >1,000-fold selectivity over Bcl-2 and Bcl-xL.
Mcl-1-IN-26 induces cleaved caspase-3 in MV4-11 cells with IC50 of 3.78 uM.
| M.Wt | 826.45 | |
| Formula | C45H52ClN5O6S | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. Johannes JW, et al. ACS Med Chem Lett. 2016 Dec 27;8(2):239-244.
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