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Chemical Structure : Meayamycin
Catalog No.: PC-62419Not For Human Use, Lab Use Only.
Meayamycin is an analogue of FR901464 that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, shows picomolar antiproliferative activity against various cancer cell lines and multidrug-resistant cells.
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Meayamycin is an analogue of FR901464 that binds to the splicing factor 3b (SF3b) complex and inhibits pre-mRNA splicing, shows picomolar antiproliferative activity against various cancer cell lines and multidrug-resistant cells.
| M.Wt | 505.652 | |
| Formula | C28H43NO7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Albert BJ, et al. Mol Cancer Ther. 2009 Aug;8(8):2308-18.
2. Visconte V, et al. Blood. 2012 Oct 18;120(16):3173-86.
3. Albert BJ, et al. J Am Chem Soc. 2007 Mar 7;129(9):2648-59.
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