Melphalan |CAS:148-82-3 Probechem Biochemicals

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Chemical Structure : Melphalan

CAS No.: 148-82-3

Melphalan (L-PAM)

Catalog No.: PC-45363Not For Human Use, Lab Use Only.

Melphalan is a chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Melphalan is a chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA.
Melphalan inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells.

Physicochemical Properties

M.Wt	305.2002
Formula	C13H18Cl2N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	DMSO: < 9.2 mg/mL
Chemical Name/SMILES	L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-

References

1. Dudek-Perić AM, et al. Cancer Res. 2015 Apr 15;75(8):1603-14.

2. Keane MM, et al. Cancer Res. 1999 Feb 1;59(3):734-41.

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Melphalan (L-PAM)

Biological Activity

Physicochemical Properties

References

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