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Memantine

Chemical Structure : Memantine

CAS No.: 19982-08-2

Memantine

Catalog No.: PC-26935Not For Human Use, Lab Use Only.

Memantine is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist with Ki of 0.19 uM for competing with [3H]MK-801 binding in membrane homogenates of postmortem human frontal cortex.

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Biological Activity

Memantine is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist with Ki of 0.19 uM for competing with [3H]MK-801 binding in membrane homogenates of postmortem human frontal cortex.

Physicochemical Properties

M.Wt 179.31
Formula C12H21N
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-amino-3,5-dimethyl-adamantane

References

1. Erdö SL, et al. Eur J Pharmacol. 1991 Jun 6;198(2-3):215-7.

2. Kornhuber J, et al. Eur J Pharmacol. 1991 Apr 25;206(4):297-300.

3. Seif el Nasr M, et al. Eur J Pharmacol. 1990 Aug 21;185(1):19-24.

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