Merbarone | Topo II inhibitor | Probechem Biochemicals

Chemical Structure : Merbarone

CAS No.: 97534-21-9

Merbarone (NSC 336628)

Catalog No.: PC-24928Not For Human Use, Lab Use Only.

Merbarone (NSC 336628) is a potent, orally active DNA topoisomerase II (Topo II) inhibitor, inhibits topoisomerase II-mediated DNA cleavage without stabilizing topo II-DNA covalent complexes.

Packing	Price	Stock
10 mg	$58	In stock
25 mg	$88	In stock
50 mg	$128	In stock
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Biological Activity

Merbarone (NSC 336628) is a potent, orally active DNA topoisomerase II (Topo II) inhibitor, inhibits topoisomerase II-mediated DNA cleavage without stabilizing topo II-DNA covalent complexes.

Physicochemical Properties

M.Wt	263.27
Formula	C11H9N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4,6-Dioxo-N-phenyl-2-thioxohexahydropyrimidine-5-carboxamide

References

1. Cooney DA, et al. Biochem Pharmacol. 1985 Sep 15;34(18):3395-8.

2. Drake FH, et al. Cancer Res. 1989 May 15;49(10):2578-83.

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Merbarone (NSC 336628)

Biological Activity

Physicochemical Properties

References

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