Mesutoclax | BCL-2 inhibitor | Probechem Biochemicals

Chemical Structure : Mesutoclax

Catalog No.: PC-25072Not For Human Use, Lab Use Only.

Mesutoclax (ICP-248) is a highly selective and potent, orally active BCL2 inhibitor.

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Biological Activity

Mesutoclax (ICP-248) is a highly selective and potent, orally active BCL2 inhibitor.

M.Wt	884.45
Formula	C45H50ClN7O8S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzamide, 4-[(3R)-4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-3-methyl-1-piperazinyl]-N-[[4-[[(2S)-1,4-dioxan-2-ylmethyl]amino]-3-nitrophenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-

1. Shuhua YI, et al. Meeting Abstract: 2025 ASCO Annual Meeting I.

2. Patent WO2022028353 A1.