Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Mevastatin
CAS No.: 73573-88-3
Catalog No.: PC-45230Not For Human Use, Lab Use Only.
Mevastatin (ML236B) is a hypolipidemic agentt that inhibits HMGCR (HMG-CoA reductase).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $58 | In stock | |
| 100 mg | $88 | In stock | |
| 500 mg | $198 | In stock | |
| 1 g | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Mevastatin (Compactin, ML-236B) is a hypolipidemic agentt that inhibits HMGCR (HMG-CoA reductase).
Mevastatin (ML236B) inhibits isoprenoid biosynthesis, blocks protein isoprenylation and reduces plasma cholesterol level.
Mevastatin (ML236B) also blcoks autolysosome maturation, stimulates LBH589-induced cell death in TNBC cells.
| M.Wt | 390.5131 | |
| Formula | C23H34O5 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)- |
|
1. Lin Z, et al. Oncotarget. 2017 Mar 14;8(11):17833-17848.
2. Brown M, et al. Br J Cancer. 2012 May 8;106(10):1689-96.
3. Zhang S, et al. Anticancer Drugs. 2010 Aug;21(7):678-86.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
