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Miconazole

Chemical Structure : Miconazole

CAS No.: 22916-47-8

Miconazole (R18134)

Catalog No.: PC-27947Not For Human Use, Lab Use Only.

Miconazole (R18134) is an imidazole antifungal agent, targets the enzyme 14 demethylase and inhibits biosynthesis of ergosterol in common fungal pathogens, also significantly reduces prostate cancer cell viability, clonogenic growth, invasion and migration, targets MCL-1 to exert an anti-leukemic effect, exhibits anti-tumor properties against multiple cancer types.

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Biological Activity

Miconazole (R18134) is an imidazole antifungal agent, targets the enzyme 14 demethylase and inhibits biosynthesis of ergosterol in common fungal pathogens, also significantly reduces prostate cancer cell viability, clonogenic growth, invasion and migration, targets MCL-1 to exert an anti-leukemic effect, exhibits anti-tumor properties against multiple cancer types.

Physicochemical Properties

M.Wt 416.12
Formula C18H14Cl4N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(2-((2,4-Dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole

References

1. Peeters F, et al. Arzneimittelforschung. 1973 Aug;23(8):1107-11.

2. Ghali ENHK, et al. ACS Omega. 2026 Jul 17;11(31):45913-45930.

3. Fang L, et al. Biochem Pharmacol. 2025 Nov;241:117126.

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