Chemical Structure : Midodrine
CAS No.: 42794-76-3
Catalog No.: PC-43176Not For Human Use, Lab Use Only.
Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension.
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Midodrine is a selective α1-adrenoceptor agonist that acts as a vasopressor/antihypotensive agent for the treatment of dysautonomia and orthostatic hypotension.
Midodrine activates the alpha-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
Midodrine does not stimulate cardiac beta-adrenergic receptors, and diffuses poorly across the blood-brain barrier.
M.Wt | 254.2823 | |
Formula | C12H18N2O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Acetamide, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]- |
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2. Pittner H, et al. Arzneimittelforschung. 1976;26(12):2145-54.
3. Kontani H, et al. Jpn J Pharmacol. 1992 Apr;58(4):339-46.
4. Brune ME, et al. J Urol. 2001 Oct;166(4):1555-9.
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