Mifepristone | Progesterone receptor antagonist

Chemical Structure : Mifepristone

CAS No.: 84371-65-3

Mifepristone (RU-486, RU486, RU38486)

Catalog No.: PC-22739Not For Human Use, Lab Use Only.

Mifepristone (RU-486, RU486) is a potent, selective progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50 of 0.2 nM and 2.6 nM respectively.

Packing	Price	Stock
100 mg	$58	In stock
250 mg	$88	In stock
500 mg	$128	In stock
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Biological Activity

Mifepristone (RU-486, RU486) is a potent, selective progesterone receptor (PR) and glucocorticoid receptor (GR) antagonist with IC50 of 0.2 nM and 2.6 nM respectively.

Physicochemical Properties

M.Wt	429.60
Formula	C29H35NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Estra-4,9-dien-3-one, 11-[4-(dimethylamino)phenyl]-17-hydroxy-17-(1-propyn-1-yl)-, (11β,17β)-

References

1. Jiang W, et al. Bioorg Med Chem. 2006 Oct 1;14(19):6726-32.

2. Juan Xu, et al. Steroids. 2020 Jul:159:108649.

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Mifepristone (RU-486, RU486, RU38486)

Biological Activity

Physicochemical Properties

References

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