Catalog No.: PC-73462Not For Human Use, Lab Use Only.
Milvexian (BMS-986177, JNJ-70033093) is a highly potent, reversible, orally bioavailable factor XIa (FXIa) inhibitor with Ki of 0.11 and 0.38 nM for human and rabbit FXIa, respectively.
Milvexian (BMS-986177, JNJ-70033093) is a highly potent, reversible, orally bioavailable factor XIa (FXIa) inhibitor with Ki of 0.11 and 0.38 nM for human and rabbit FXIa, respectively.
Milvexian (BMS-986177, JNJ-70033093) increased activated partial thromboplastin time (APTT) without changing prothrombin time and potently prolonged plasma APTT in humans and rabbits.
Milvexian (BMS-986177, JNJ-70033093) is an effective antithrombotic agent with limited impact on hemostasis, even when combined with aspirin in rabbits.
Milvexian (BMS-986177, JNJ-70033093) is a clinical candidate for the prevention and treatment of thromboembolic disorders.
