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Chemical Structure : Min-1
Catalog No.: PC-20704Not For Human Use, Lab Use Only.
Min-1 is small molecule that inhibits growth of Gram-positive bacteria by targeting the cell envelope, Min-1 is a novel inhibitor of bacterial growth, reduces cell size in Bacillus subtilis.
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Min-1 is small molecule that inhibits growth of Gram-positive bacteria by targeting the cell envelope, Min-1 is a novel inhibitor of bacterial growth, reduces cell size in Bacillus subtilis.
Min-1 inhibits growth of Gram-positive bacteria and reduces cell length of B. subtilis (MIC=31 uM, B. subtilis JH642 (LB)).
Min-1 disrupts coordination between growth and FtsZ ring assembly independent of known cell size mechanisms.
Min-1 activates the LiaRS stress response, which is sensitive to disruptions in the lipid II cycle and the cell membrane, and also compromises cell membrane integrity.
| M.Wt | 336.27 | |
| Formula | C16H11F3N2O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Scott McAuley, et al. ACS Chem Biol. 2019 Apr 19;14(4):688-695.
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