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Minocycline hydrochloride

Chemical Structure : Minocycline hydrochloride

CAS No.: 13614-98-7

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Minocycline hydrochloride

Catalog No.: PC-45234Not For Human Use, Lab Use Only.

Minocycline hydrochloride is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects, inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, also is a hypoxia-inducible factor (HIF)-1α inhibitor.

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250 mg $78 In stock
1 g $158 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Minocycline hydrochloride is a tetracycline antibiotic with neuroprotective, antiapoptotic, anti-inflammatory and antimicrobial effects, inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, also is a hypoxia-inducible factor (HIF)-1α inhibitor.

Physicochemical Properties

M.Wt 493.9373
Formula C23H28ClN3O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O: 2.45 mg/mL; DMSO: 0.49 mg/mL
Chemical Name/SMILES

2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aR,12aS)-

References

1. Hu X, et al. Eur J Pharmacol. 2011 Mar 11;654(3):274-9.

2. Padi SS, et al. Eur J Pharmacol. 2008 Dec 28;601(1-3):79-87.

3. Venniyoor A, et al. Front Oncol. 2016 Oct 27;6:231.

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