Mtb GuaB-IN-2

Chemical Structure : Mtb GuaB-IN-2

Catalog No.: PC-28181Not For Human Use, Lab Use Only.

Mtb GuaB-IN-2 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, IMPDH) with IC50 of 0.2 nM.

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Biological Activity

Mtb GuaB-IN-2 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, IMPDH) with IC50 of 0.2 nM.

Physicochemical Properties

M.Wt	412.44
Formula	C22H22F2N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-Pyrano[3,4-c]quinoline, 9-[(1R)-1-[1-[3-(difluoromethyl)bicyclo[1.1.1]pent-1-yl]-1H-1,2,3-triazol-4-yl]ethoxy]-1,4-dihydro-

References

1. Sabnis RW. ACS Med Chem Lett. 2025 Oct 30;16(11):2204-2205.

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Mtb GuaB-IN-2

Biological Activity

Physicochemical Properties

References

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