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Mycobacidin

Chemical Structure : Mycobacidin

CAS No.: 539-35-5

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Mycobacidin (Actithiazic acid, Acidomycin)

Catalog No.: PC-25838Not For Human Use, Lab Use Only.

Mycobacidin (Acidomycin, Actithiazic acid) is a promising antitubercular activity against a series of contemporary drug susceptible and drug-resistant M. tuberculosis strains with MICs of 0.096-6.2 uM, inhibits biotin synthesis with a Ki of approximately 1 μM through the competitive inhibition of biotin synthase (BioB).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Mycobacidin (Acidomycin, Actithiazic acid) is a promising antitubercular activity against a series of contemporary drug susceptible and drug-resistant M. tuberculosis strains with MICs of 0.096-6.2 uM, inhibits biotin synthesis with a Ki of approximately 1 μM through the competitive inhibition of biotin synthase (BioB).

Physicochemical Properties

M.Wt 217.28
Formula C9H15NO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-(4-Oxothiazolidin-2-yl)hexanoic acid

References

1. Bockman MR, et al. ACS Infect Dis. 2019 Apr 12;5(4):598-617.

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