Myosin-5 inhibitor G19

Chemical Structure : Myosin-5 inhibitor G19

Catalog No.: PC-25311Not For Human Use, Lab Use Only.

Myosin-5 inhibitor G19 is a potent small molecule inhibitor of Myosin-5 in fungi, shows EC50 value of 0.326 μg/mL against Fusarium graminearum (Fg).

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Biological Activity

Myosin-5 inhibitor G19 is a potent small molecule inhibitor of Myosin-5 in fungi, shows EC50 value of 0.326 μg/mL against Fusarium graminearum (Fg).
G19 severely damaged the surface integrity of mycelial cells and induced cytoplasmic leakage.
G19 stably binds to the target protein Myosin-5 in a mode similar to that of phenamacril.
G19 exhibits in vivo antifungal activity and curative effects against phytopathogenic fungi.

Physicochemical Properties

M.Wt	301.30
Formula	C16H15NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl (E)-3-(furan-2-carboxamido)-2-hydroxy-3-phenylacrylate

References

1. Hou ST, et al. J Agric Food Chem. 2025 Aug 6. doi: 10.1021/acs.jafc.5c01840.

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