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Myricetin

Chemical Structure : Myricetin

CAS No.: 529-44-2

Myricetin (Cannabiscetin, Myricetol, Myricitin)

Catalog No.: PC-72237Not For Human Use, Lab Use Only.

Myricetin (Myricetol, Myricitin) is a flavonoid compound with antioxidant properties, inhibits ENPP1 enzymatic activity with IC50 of 4.8 uM.

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Biological Activity

Myricetin (Myricetol, Myricitin) is a flavonoid compound with antioxidant properties, inhibits ENPP1 enzymatic activity with IC50 of 4.8 uM.
Myricetin demonstrate significant improvement in heart function after injury in treated animal models.
Myricetin exhibited selective inhibition of cell growth (IC50 114.75 uM) and induced apoptosis in MDA-MB-231 cells.
Myricetin act as potential inhibitors of key tumorigenic signaling pathways, such as PI3K/Akt/mTOR, p38 MAPK and NF-κB. decrease the intracellular levels of ROS and pro-inflammatory cytokines, such as TNF-α, IL-1β and IL-6.

Physicochemical Properties

M.Wt 318.237
Formula C15H10O8
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one

References

1. Shen Li, et al. J Clin Invest. 2022 Jan 18;132(2):e149711.

2. Sousa C, et al. Nutr Cancer. 2021 Nov 5:1-15.

3. Vukovic NL, et al. Food Res Int. 2018 Apr;106:71-80.

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