Myricoside

Chemical Structure : Myricoside

CAS No.: 76076-04-5

Catalog No.: PC-26819Not For Human Use, Lab Use Only.

Myricoside is a phenylethanoid triglycoside from Phlomis oppositiflora and small molecule β‑1,4‑galactosyltransferase III (B4GALT3) inhibitor.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$348	In stock
50 mg		Get quote
100 mg		Get quote

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Biological Activity

Myricoside is a phenylethanoid triglycoside from Phlomis oppositiflora and small molecule β‑1,4‑galactosyltransferase III (B4GALT3) inhibitor.
Myricoside occupies the catalytic pocket of B4GALT3, forming hydrogen bonds with key residues (Asp195, Asp197, His291, Asp294) and hydrophobic interactions.
Myricoside induced dose-dependent RB cell death, reduced fibronectin adhesion, decreased β1-integrin galactosylation, and suppressed the FAK–PI3K–AKT–Bcl2 axis, mimicking the effects of B4GALT3 knockdown.
Myricoside attenuated proptosis and corneal neovascularization, and significantly reduced tumor size and invasiveness in orthotopic retinoblastoma xenograft model.

Physicochemical Properties

M.Wt	756.71
Formula	C34H44O19
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R,4R,5R,6R)-4-(((2S,3R,4R,5S,6S)-4-(((2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl (E)-3-(3,4-dihydroxyphenyl)acrylate

References

1. Tang J, et al. Cell Death Dis. 2026 Mar 23;17(1):336.

2. Caliş I, et al. Nat Prod Res. 2005 Jul;19(5):493-501.

Myricoside

Biological Activity

Physicochemical Properties

References

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