Chemical Structure : N-Acetyl-Calicheamicin
CAS No.: 108212-76-6
Catalog No.: PC-45713Not For Human Use, Lab Use Only.
N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic, targets DNA and causes strand scission, N-Acetyl-Calicheamicin is a ADC payload in antibody drug conjugates development.
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N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic, targets DNA and causes strand scission, N-Acetyl-Calicheamicin is a ADC payload in antibody drug conjugates development.
M.Wt | 1410.385 | |
Formula | C57H76IN3O22S4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Carbamic acid, [(1R,4Z,8S,13E)-8-[[2-O-[4-(acetylethylamino)-2,4-dideoxy-3-O-methyl-α-L-threo-pentopyranosyl]-4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyrano |
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2. Naito K, et al. Leukemia. 2000 Aug;14(8):1436-43.
3. Hills RK, et al. Lancet Oncol. 2014 Aug;15(9):986-96.
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