Chemical Structure : N-Desethyl Sunitinib
CAS No.: 356068-97-8
Catalog No.: PC-42725Not For Human Use, Lab Use Only.
The active metabolite of sunitinib, which is an oral, small-molecule, multi-targeted RTKs inhibitor for the treatment of RCC and imatinib-resistant GIST..
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The active metabolite of sunitinib, which is an oral, small-molecule, multi-targeted RTKs inhibitor for the treatment of RCC and imatinib-resistant GIST.
M.Wt | 370.4206 | |
Formula | C20H23FN4O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1H-Pyrrole-3-carboxamide, N-[2-(ethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl- |
1. Chen X, et al. Biomed Chromatogr. 2015 May;29(5):679-88.
2. Lankheet NA, et al. Br J Cancer. 2014 May 13;110(10):2441-9.
3. Tang SC, et al. J Pharmacol Exp Ther. 2012 Apr;341(1):164-73.
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