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Chemical Structure : N-butylidenephthalide
Catalog No.: PC-61325Not For Human Use, Lab Use Only.
A natural compound derived from Angelica sinensis that inhibits malignant brain tumor growth in vitro and in vivo.
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A natural compound derived from Angelica sinensis that inhibits malignant brain tumor growth in vitro and in vivo; upregulates the expression of p21 and p27, decrease sphosphorylation of Rb proteins, causes cell arrest at the G0/G1 phase in GBM tumor cells; inhibits the expression of Axl and reduces the migratory and invasive capabilities of GBM cells; inhibits tumour growth and suppresses Axl expression in tumour models.
| M.Wt | 188.226 | |
| Formula | C12H12O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yen SY, et al. Oncogene. 2016 Apr 28;35(17):2156-65.
2. Lin PC, et al. J Neurochem. 2008 Aug;106(3):1017-26.
3. Tsai NM, et al. J Neurochem. 2006 Nov;99(4):1251-62.
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