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N3PT

Chemical Structure : N3PT

CAS No.: 13860-66-7

N3PT (N3-pyridyl thiamine)

Catalog No.: PC-24830Not For Human Use, Lab Use Only.

N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor, N3PT is pyrophosphorylated and then binds to transketolase with Kd of 22 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor, N3PT is pyrophosphorylated and then binds to transketolase with Kd of 22 nM.

Physicochemical Properties

M.Wt 336.28
Formula C13H19Cl2N3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((2-Amino-6-methylpyridin-3-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride hydrochloride

References

1. Thomas AA, et al. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2206-10.

2. Thomas AA, et al. Bioorg Med Chem Lett. 2008 Jan 15;18(2):509-12.

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