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NBD-14189

Chemical Structure : NBD-14189

CAS No.: 2234273-72-2

NBD-14189 (NBD14189)

Catalog No.: PC-35225Not For Human Use, Lab Use Only.

NBD-14189 (NBD14189) is a novel potent HIV-1 entry antagonist with IC50 of 89 nM against the HIV-1HXB2 pseudovirus, target HIV-1 gp120.

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    Biological Activity

    NBD-14189 (NBD14189) is a novel potent HIV-1 entry antagonist with IC50 of 89 nM against the HIV-1HXB2 pseudovirus, target HIV-1 gp120.

    Physicochemical Properties

    M.Wt 428.406
    Formula C18H16F4N4O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(2-amino-1-(4-(hydroxymethyl)thiazol-2-yl)ethyl)-5-(3-fluoro-4-(trifluoromethyl)phenyl)-1H-pyrrole-2-carboxamide

    References

    1. Curreli F, et al. Eur J Med Chem. 2018 Jun 25;154:367-391.

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