Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-HIV-NBD-14270
NBD-14270

Chemical Structure : NBD-14270

CAS No.: 2646671-34-1

Add to Favorites

NBD-14270 (NBD14270)

Catalog No.: PC-72614Not For Human Use, Lab Use Only.

NBD-14270 (NBD14270) is an HIV-1 gp120 antagonist, shows antiviral activity against HIV-1HXB2 with IC50 of 180 nM.

Packing Price Stock Quantity
25 mg Get quote
50 mg Get quote
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    NBD-14270 (NBD14270) is an HIV-1 gp120 antagonist, shows antiviral activity against HIV-1HXB2 with IC50 of 89 nM.
    NBD-14270 showed broad-spectrum antiviral activitiesa large panel of diverse HIV-1 Env-pseudotyped clinical isolates (mean IC50=0.18 uM), neutralized both the infant and maternal HIV-1 variants with mean IC50 of 0.37 uM.

    Physicochemical Properties

    M.Wt 425.43
    Formula C18H18F3N5O2S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(2-amino-1-(5-(hydroxymethyl)thiazol-2-yl)ethyl)-3-methyl-5-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-carboxamide

    References

    1. Curreli F, et al. J Med Chem. 2020 Feb 27;63(4):1724-1749.

    Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    Contact Us sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    Get Quote

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • Additional Information: