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Chemical Structure : NBD-14273
Catalog No.: PC-73246Not For Human Use, Lab Use Only.
NBD-14273 is a CD4-mimetic, small-molecule HIV-1 entry inhibitor with IC50 of 0.13 uM.
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NBD-14273 is a CD4-mimetic, small-molecule HIV-1 entry inhibitor with IC50 of 0.13 uM.
NBD-14273 showed both improved antiviral activity and selectivity index (SI) against HIV-1HXB2 compared to NBD-14136.
NBD-14273 displayed potenct against a large panel of 50 HIV-1 Env-pseudotyped viruses representing clinical isolates of diverse subtypes.
| M.Wt | 442.433 | |
| Formula | C19H18F4N4O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Francesca Curreli, et al. Bioorg Med Chem. 2021 Feb 15;32:116000.
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