Chemical Structure : NBI-27914
CAS No.: 184241-44-9
Catalog No.: PC-21398Not For Human Use, Lab Use Only.
NBI-27914 is a potent, selective antagonist of corticotropin-releasing factor 1 (CRF1) receptor with Ki of 1.7 nM, shows no activity at CRF2 receptors.
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NBI-27914 is a potent, selective antagonist of corticotropin-releasing factor 1 (CRF1) receptor (CRFR1, CRF-R1) with Ki of 1.7 nM, shows no activity at CRF2 receptors.
M.Wt | 434.19 | |
Formula | C18H20Cl4N4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-Chloro-N-(cyclopropylmethyl)-2-methyl-N-propyl-N'-(2,4,6-trichlorophenyl)-4,6-pyrimidinediamine |
1. T Z Baram, et al. Brain Res. 1997 Oct 3;770(1-2):89-95.
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