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Chemical Structure : NBQX
CAS No.: 118876-58-7
Catalog No.: PC-61719Not For Human Use, Lab Use Only.
NBQX is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM.
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| 10 mg | $138 | In stock | |
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NBQX is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM.
NBQX binds to the quisqualate subtype of the glutamate receptor, with no activity at the NMDA and glycine sites.
NBQX also blocks kainate receptor with IC50 of 4.8 uM.
NBQX exhibits anticonvulsant activity in rodent seizure models.
| M.Wt | 336.28 | |
| Formula | C12H8N4O6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide |
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1. Sheardown MJ, et al. Science. 1990 Feb 2;247(4942):571-4.
2. Klockgether T, et al. Ann Neurol. 1991 Nov;30(5):717-23.
3. Gill R, et al. Brain Res. 1992 May 15;580(1-2):35-43.
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