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NBQX disodium

Chemical Structure : NBQX disodium

CAS No.: 479347-86-9

NBQX disodium

Catalog No.: PC-61720Not For Human Use, Lab Use Only.

NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM; exhibits anticonvulsant activity in rodent seizure models.

Physicochemical Properties

M.Wt 380.24
Formula C12H6N4O6SNa2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt

References

1. Sheardown MJ, et al. Science. 1990 Feb 2;247(4942):571-4.

2. Klockgether T, et al. Ann Neurol. 1991 Nov;30(5):717-23.

3. Gill R, et al. Brain Res. 1992 May 15;580(1-2):35-43.

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