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NBQX disodium

Chemical Structure : NBQX disodium

CAS No.: 479347-86-9

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NBQX disodium

Catalog No.: PC-61720Not For Human Use, Lab Use Only.

NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM.
NBQX disodium exhibits anticonvulsant activity in rodent seizure models.

Physicochemical Properties

M.Wt 380.24
Formula C12H6N4O6SNa2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

100 mM in H2O
Chemical Name/SMILES

2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt

References

1. Sheardown MJ, et al. Science. 1990 Feb 2;247(4942):571-4.

2. Klockgether T, et al. Ann Neurol. 1991 Nov;30(5):717-23.

3. Gill R, et al. Brain Res. 1992 May 15;580(1-2):35-43.

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